CoLocalizer Pro 7.1.1 (2026.05.05)
- 🧭 Inspector, Background Correction, and Colocalization menu items have been moved into a submenu under Tools > Analysis for better organization.
- 🔄 The slice panel now opens automatically the first time a multi-slice image is opened.
- ✨ Optimized image rendering for Retina and High-DPI displays: the Region of Interest (ROI) now respects system scaling, ensuring images are displayed at the correct physical size with maximum sharpness.
- ♻️ Added a Reset button in ROI Settings to quickly restore the Selection Line Color to its default.
- ✅ Multi-slice reordering was not persisting across saves - fixed.
- 🔧 When deleting slices in an image stack, the Inspector did not update the number of remaining slices correctly - fixed.
- ⚙️ Made various stability and performance enhancements.
CoLocalizer Pro 7.1 (2026.04.02)
- 🚀 Now uses Metal compute shaders for better performance and efficiency.
- ✨ 16-bit TIFFs can now be opened and analyzed correctly, with intensity relationships preserved.
- 🖼️ Rectangular images appeared distorted in square-sized background correction presets - fixed.
- 🤌 Trackpad zoom is now smoother and more consistent.
- ⚙️⚙️ Made various stability and performance enhancements.
CoLocalizer Pro 7.0.7 (2026.03.03)
- Unified alert behavior when exporting calculation results and splitting files: the alert now shows the full folder path if the folder already exists, so users know exactly which folder will affected.
- When undoing/redoing channel pair selections, the specific channel pair name is now shown instead of the generic “Channel Pair” label.
- When selecting source images for merging, the app now remembers the last folder you chose, reducing repeated navigation.
- In exported colocalization report notes, you can now use any Unicode characters, including emoji.
- When exporting calculation results, users will now see an alert if no items are selected for export.
- Made various security, performance, and UI enhancements.
- Now requires macOS 13 (Ventura) or newer.
CoLocalizer Pro 7.0.6 (2025.12.17)
- Edits to images are now reliably saved when closing and reopening documents.
- Splitting according to channels is now faster, especially for larger files.
- When connected via USB to a microscope or iPad, the importer window now updates its title dynamically.
- When exporting calculation results, if a path other than the default one in Settings is chosen, it will be reset to the Settings path for the next export.
- Fixed an issue where, even when the Reveal Pixels switch in the Colocalization panel was turned off, images with revealed pixels were still exported and added to reports.
- Help Viewer now prioritizes consistency and quick orientation over restoring the previous state.
- Improved the layout of exported XLSX files to match the styling of PDF and HTML reports.
- During merge of color channels, invalid file drops now show the filename and supported formats, and successful merges display a brief, auto-dismissing confirmation.
- When splitting images according to selected channels, the full folder path when a folder already exists is shown in the alert, so users know exactly which folder will be affected.
- Improved date readability in the Inspector.
- You can now see a live preview of your new ROI selection line color instantly while adjusting it in the Settings window.
- The app icon has been refreshed with a sleek, modern Liquid Glass look.
- Select UI elements now use modern SwiftUI.
- Made various performance and security enhancements.
- Made various updates and UI improvements to support changes introduced in macOS 26 (Tahoe).
- Now requires macOS 12 (Monterey) or newer.
CoLocalizer Pro 7.0.5 (2025.07.22)
- When saving split channel images, the legacy image-saving panel was replaced with a folder-saving panel, since split images are always saved in folders regardless of their number. File format options are still available in the new panel.
- When exporting and saving images, the app didn't remember its previous path. Fixed.
- Position of the label indicating the size of the ROI wasn't properly set. Fixed.
- Successful merging of image channels is now confirmed by the success alert.
- k1, k2, m1, m2, M1, M2 coefficients labels in the Colocalization View are now displayed with subscripts.
- When renewing a license, subscribers are now automatically directed from the “License Will Expire” alert to the discount store.
- Improved built-in Help access: the Help contents appear automatically after network access is restored, saving you time.
- Made various security, performance, and UI enhancements.
CoLocalizer Pro 7.0.4 (2025.06.26)
CoLocalizer Pro 7.0.2 (2021.08.13)
- The redesigned architecture of the ML Super Resolution model significantly decreased the use of system memory: now requires 7.5 times less RAM.
CoLocalizer Pro 7.0.1 (2021.01.19)
- Added support for macOS 11 (Big Sur).
- New macOS 11 style app icon.
- Now requires macOS 10.15 (Catalina) or newer to support Machine Learning.
CoLocalizer Pro 7.0 (2020.08.04)
- Introducing ML Super Resolution. Revolutionary Machine Learning-powered transformation of conventional fluorescence images to images comparable with super resolution.
- Now requires macOS 10.13 (High Sierra) or newer.
CoLocalizer Pro 6.1 (2020.05.05)
- The prediction accuracy of the Background Correction model has improved to 99%.
- When changing channel pairs with Reveal Colocalized Pixels selected, pixels on the image were not updated. Fixed.
- It is now possible to export either uncompressed or compressed (LZW, Packbits) TIFF files.
- Improved layout of the report files.
CoLocalizer Pro 6.0 (2019.12.21)
- Introducing Machine Learning-enhanced background correction. The Deep Learning model provides over 90% prediction accuracy of various background noise levels.
- Redesigned Background Correction pane, and updated tooltips.
- Histogram channels are now shown more distinctively.
- Updated to the latest version of Sparkle update framework.
- Updated graphics.
